Why do American Products Contain Food Dyes that are Banned in Other Countries?

Some of the most well-known food additives on the market are high fructose corn syrup (HFCS), monosodium glutamate (MSG), and sucralose (Splenda). Here’s a brief review of what I find patients to be consuming a lot:

  • HFCS is a nutritive sweetener made of fructose and glucose.  It is extracted from corn and commonly added to sodas, fruit-flavored drinks, and baked goods. 

  • MSG is a flavoring derived from the fermentation of molasses, cane sugar and sugar beets. It is commonly found in many Asian dishes, canned vegetables, and soups.  Since MSG cannot be easily digested and used for cellular energy, it causes a great deal of harm to the human body.  

  • Splenda is a non-nutritive sweetener prevalent in many foods including dairy products, cereals, diet foods, beverages, and condiments. Its main ingredient, Sucralose, is 600 times sweeter than sucrose. Several studies found sucralose to alter blood glucose, insulin response, and gut flora while others found no effect on hormones, gut flora, or carcinogenesis. Unfortunately, industry ties may indicate bias in the Magnuson study finding no harm.

Food dyes (aka., artificial coloring) are used in many foods and pharmaceuticals in order to help make them more appealing and recognizable.  If a food, tablet, liquid or capsule is recognizably colored, it makes it more readily identified both as a food, dispensing of the medication, and when advertising the product. 

Do remember that pharmaceutical medications are products just like sodas, candy bars, and automobiles. There’s billions of dollars invested in “branding” a product to make it more recognizable and desirable, ultimately to increase sales and profits for the parent company. 

They dyes have been extensively studies in North America and Europe, and found to be extremely detrimental to human health.  They have been banned in many European countries but legal in the U.S. FOOD and PHARMACEUTICAL INDUSTRY since the artificial coloring better entice consumers to ultimately drive a profit, even at the expense of the public’s health.

Common Foods Which Often Contain Artificial Coloring are: 

  • Jellies

  • Puddings

  • Juices and other beverages

  • Jams

  • Condiments

  • Chewing gum

  • Candy

  • Dairy

  • Baked goods. 

Prescription medicines are often distinctively shaped and colored to differentiate themselves from other brands or to indicate dosage. This has the benefit of cutting down on mistakes while dispensing medications. The problem is many of the dyes are extremely harmful.  

Red dye #40, also known as Allura Red AC, is derived from petroleum distillates or coal tars.  It contains benzidine, a known carcinogen also known to cause ADHD and behavioral issues in children.  It is  commonly used in many OTC and prescribed medicationsRefer to this link to learn more about Red Dye #40 containing medications and foods.  Being better informed will help you know which foods and medications to avoid since their associated side effects are often caused by their toxic inactive ingredients.  

Dye Yellow #5, also known as Tartrazine.  Tartrazine is an organic sodium salt (i.e. the trisodium salt of tartrazine acid).  When ingested, Tartrazine is reduced to sulfanylic acid. Sulfanylic acid often causes allergic reactions, including urticaria (hives), asthma, blood spots/skin hemorrhages, and eczema. Those most sensitive to Dye Yellow #5 often also have an aspirin allergy, indicating a genetic susceptibility.  This is why countries like Sweden, Switzerland, and Norway have withdrawn Tartrazine on the grounds of its anaphylactic potential. The United States has not.

 

Doctor’s Advice

The old adage applies here:  Less is More. 

Changing the American mindset is valuable. Shifting to a whole foods plant-based diet where you often cook your food from scratch will help you not only avoid tons of toxic additives, but immediately start helping you feel well.  

 

 

References

Bray, G. A., et al. (2004). "Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity." Am J Clin Nutr 79(4): 537-543.

Chung, K. T., Stevens, S. E., & Cerniglia, C. E. (1992). The reduction of azo dyes by the intestinal microflora. Critical reviews in microbiology, 18(3), 175-190.

Clydesdale, F. M. (1993). Color as a factor in food choice. Critical reviews in food science and nutrition, 33(1), 83-101.

Corder, E. H., & Buckley III, C. E. (1995). Aspirin, salicylate, sulfite and tartrazine induced bronchoconstriction. Safe doses and case definition in epidemiological studies. Journal of clinical epidemiology, 48(10), 1269-1275.

Desmond, R. E., & Trautlein, J. J. (1981). Tartrazine (FD & C yellow# 5) anaphylaxis: a case report. Annals of allergy, 46(2), 81-82.

Devlin, J., & David, T. J. (1992). Tartrazine in atopic eczema. Archives of disease in childhood, 67(6), 709-711.

Freeman, M. (2006). Reconsidering the effects of monosodium glutamate: a literature review. Journal Of The American Academy Of Nurse Practitioners18(10), 482-486. 

Montaño García, M. L., & Orea, S. (1989). Estudio de la frecuencia de urticaria y angioedema inducidos por aditivos de alimentos. Alergia Méx, 36(1), 15-8.

Goran, M. I., et al. (2013). "High fructose corn syrup and diabetes prevalence: a global perspective." Glob Public Health 8(1): 55-64.

Jones, R., Ryan, AJ. and Wright, S. E. (1964). The metabolism and excretion of tartrazine. Food Cosmet Toxicol., vol. 2, 447p.

Maekawa, A., Matsuoka, C., Onodera, H., Tanigawa, H., Furuta, K., Kanno, J., ... & Ogiu, T. (1987). Lack of carcinogenicity of tartrazine (FD & C Yellow No. 5) in the F344 rat. Food and Chemical Toxicology, 25(12), 891-896.

Magnuson, B. A., Roberts, A., & Nestmann, E. R. (2017). Critical review of the current literature on the safety of sucralose. Food and Chemical Toxicology,106, 324-355.

Meadows, M. (2003). MSG: a common flavor enhancer. monosodium glutamate. FDA Consumer37(1), 34-35. 

Pepino, Y., Tiemann, C., Patterson, B., Wice, B., & Klein, S. (2013). Sucralose Affects Glycemic and Hormonal Responses to an Oral Glucose Load. Diabetes Care.

Potera, C. (2010).  Diet and Nutrition:  The artificial food dye blues. Environmental health perspectives, 118(10). 

PubChem. (2019a). "Tartrazine | C16H9N4Na3O9S2". Date Modified: March 23, 2019. Retrieved April 25, 2019 from https://pubchem.ncbi.nlm.nih.gov/compound/Tartrazine

Roxon, J. J., Ryan, A. J., & Wright, S. E. (1967). Enzymatic reduction of tartrazine by Proteus vulgaris from rats. Food and cosmetics toxicology, 5, 645-656.

Samuels, A. (1999). The toxicity/safety of processed free glutamic acid (MSG): a study in suppression of information. Accountability in Research, 6(4), 259-310. 

Schiffman, S. S., & Rother, K. I. (2013). Sucralose, A Synthetic Organochlorine Sweetener: Overview of Biological Issues. Journal of Toxicology and Environmental Health. Part B, Critical Reviews16(7), 399–451. 

Stanhope, K. L., et al. (2015). "A dose-response study of consuming high-fructose corn syrup-sweetened beverages on lipid/lipoprotein risk factors for cardiovascular disease in young adults." Am J Clin Nutr 101(6): 1144-1154. 

U.S. Department of Health and Human Services (2007).  Summary of color additives listed for use in the United States in food, drugs, cosmetics and medical devices.   Retrieved from https://web.archive.org/web/20071216000102/http://www.cfsan.fda.gov:80/~dms/opa-col2.html#table1A. 

U.S. Food and Drug Administration (FDA). (2014). High Fructose Corn Syrup: Questions and Answers. Retrieved from https://www.fda.gov/food/ingredientspackaginglabeling/foodadditivesingredients/ucm324856.htm 

Weiner, M. L. (2014). Food additive carrageenan: Part II: a critical review of carrageenan in vivo safety studies. Critical Review of Toxicology44, 244-269. 

Wüthrich, B. (1993). Adverse reactions to food additives. Annals of allergy, 71(4), 379-384.

AUTHOR

Dr. Payal Bhandari M.D. is one of U.S.'s top leading integrative functional medical physicians and the founder of SF Advanced Health. She combines the best in Eastern and Western Medicine to understand the root causes of diseases and provide patients with personalized treatment plans that quickly deliver effective results. Dr. Bhandari specializes in cell function to understand how the whole body works. Dr. Bhandari received her Bachelor of Arts degree in biology in 1997 and Doctor of Medicine degree in 2001 from West Virginia University. She the completed her Family Medicine residency in 2004 from the University of Massachusetts and joined a family medicine practice in 2005 which was eventually nationally recognized as San Francisco’s 1st patient-centered medical home. To learn more, go to www.sfadvancedhealth.com.